{"id":276,"date":"2020-07-22T19:12:02","date_gmt":"2020-07-22T18:12:02","guid":{"rendered":"https:\/\/www.kardiohirurgija.rs\/o-srcu\/"},"modified":"2020-08-19T22:58:55","modified_gmt":"2020-08-19T21:58:55","slug":"on-heart","status":"publish","type":"page","link":"https:\/\/www.kardiohirurgija.rs\/en\/on-heart\/","title":{"rendered":"On Heart"},"content":{"rendered":"<p>[vc_row type=&#8221;vc_default&#8221; css=&#8221;.vc_custom_1474218751979{padding-bottom: 50px !important;}&#8221;][vc_column][vc_raw_html]JTNDc3BhbiUyMGlkJTNEJTIyYW5hdG9taWphLWZ1bmtjaWphJTIyJTIwc3R5bGUlM0QlMjJwb3NpdGlvbiUzQSUyMHJlbGF0aXZlJTNCJTIwdG9wJTNBJTIwLTEwMHB4JTNCJTIyJTNFJTNDJTJGc3BhbiUzRQ==[\/vc_raw_html]<div id=\"ultimate-heading-32976a3498156c01e\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-32976a3498156c01e uvc-8472  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-32976a3498156c01e h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"font-weight:bold;margin-bottom:20px;\">HUMAN HEART ANATOMY AND PHYSIOLOGY<\/h2><\/div><\/div>[vc_column_text css=&#8221;.vc_custom_1595543659438{padding-bottom: 20px !important;}&#8221;]The heart is located behind the chest bone and slightly displaced to the left side. It is a hollow muscular organ that is pumping the blood throughout our body. The heart consists of two atria and two ventricles. Four heart valves alternatively open and closes during the heart cycle, providing the unilateral blood through the heart chambers. The tricuspid valve is positioned between the right atrium and the ventricle while the pulmonary valve is located between the right ventricle and the pulmonary artery. Those valves are located on the right side of the heart, pumping the venous blood to be oxygenated in the lungs. The left heart side is pumping oxygen-rich blood that is coming from lungs throughout our body. The Mitral valve is located between the left atrium and ventricle, while the aortic valve is between the heart and the aorta.[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/2&#8243;][vc_column_text]The heart cycle consists of alternate contractions and relaxations, known as systole and diastole. The average human heart beats 60 &#8211; 100 beats per minute, and ejects around 70 ml of blood with each contraction, making 5 liters of blood pumped every minute in the average person of 75 kg. The blood is ejected into the aorta, the biggest arterial blood vessel in a human body. Aortic branches, after that, provide blood delivery to the head, limbs, and organs. Coronary arteries, the first aortic branches, perfuse the heart.[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/2&#8243; css=&#8221;.vc_custom_1588624703199{padding-left: 50px !important;}&#8221; offset=&#8221;vc_hidden-xs&#8221;][vc_single_image image=&#8221;503&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;link_image&#8221;][\/vc_column][vc_column][vc_column_text]<\/p>\n<div class=\"hr-thin\"><\/div>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row full_width=&#8221;stretch_row&#8221; type=&#8221;vc_default&#8221; css=&#8221;.vc_custom_1588624603642{padding-bottom: 50px !important;}&#8221;][vc_column el_id=&#8221;angina&#8221;][vc_raw_html]JTNDc3BhbiUyMGlkJTNEJTIyYW5naW5hJTIyJTIwc3R5bGUlM0QlMjJwb3NpdGlvbiUzQSUyMHJlbGF0aXZlJTNCJTIwdG9wJTNBJTIwLTEwMHB4JTNCJTIyJTNFJTNDJTJGc3BhbiUzRQ==[\/vc_raw_html]<div id=\"ultimate-heading-5386a3498156c12f\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-5386a3498156c12f uvc-295  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-5386a3498156c12f h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"font-weight:bold;margin-bottom:20px;\">ANGINA PECTORIS<\/h2><\/div><\/div>[\/vc_column][vc_column width=&#8221;5\/12&#8243;][vc_column_text]Angina pectoris is a symptom of coronary arteries stenosis. Atherosclerosis obstructs the arteries by cholesterol plaques that are reducing the blood delivery to the myocardium. During the physical activity, insufficient oxygen delivery to the myocardium results in chest angina pain, which eventually subsides during the rest. The pain could spread up to the jaw or down the arm. That is stable angina pectoris. In advanced disease, chest pain will appear even during the rest. Now we are talking about unstable angina. If untreated unstable angina eventually results in myocardial infarction.[\/vc_column_text][\/vc_column][vc_column width=&#8221;7\/12&#8243;][vc_single_image image=&#8221;392&#8243; img_size=&#8221;full&#8221;][\/vc_column][vc_column][vc_column_text]<\/p>\n<div class=\"hr-thin\"><\/div>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row full_width=&#8221;stretch_row&#8221; type=&#8221;vc_default&#8221; css=&#8221;.vc_custom_1588624612311{padding-bottom: 50px !important;}&#8221;][vc_column][vc_row_inner][vc_column_inner width=&#8221;1\/3&#8243;][\/vc_column_inner][vc_column_inner width=&#8221;2\/3&#8243;]<div id=\"ultimate-heading-62436a3498156c20d\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-62436a3498156c20d uvc-3266  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-62436a3498156c20d h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"font-weight:bold;margin-bottom:20px;\">MYOCARDIAL INFARCTION<\/h2><\/div><\/div>[\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;393&#8243; img_size=&#8221;full&#8221; onclick=&#8221;link_image&#8221;][\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_column_text]Myocardial infarction is a permanent heart muscle damage. It could develop suddenly, due to coronary arteries thrombosis or gradually during the chest angina.\u00a0 Patients with myocardial infarction experience excruciating chest pain, sweating and fall in blood pressure, frequently followed by arrhythmias. If severe, infarction could result in a shock and sometimes death.<\/p>\n<p>Myocardial damage is permanent, and symptoms in those who survive to depend on the infarction extent. Reduced physical activity, arrhythmias, heart failure, and mitral valve insufficiency are some severe complications.[\/vc_column_text][\/vc_column][vc_column][vc_column_text]<\/p>\n<div class=\"hr-thin\"><\/div>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row full_width=&#8221;stretch_row&#8221; type=&#8221;vc_default&#8221; css=&#8221;.vc_custom_1588624603642{padding-bottom: 50px !important;}&#8221;][vc_column]<div id=\"ultimate-heading-18946a3498156c2ed\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-18946a3498156c2ed uvc-5311  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-18946a3498156c2ed h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"font-weight:bold;margin-bottom:20px;\">ATHEROSCLEROSIS PREVENTION<\/h2><\/div><\/div>[\/vc_column][vc_column width=&#8221;5\/12&#8243;][vc_column_text]High blood pressure, diabetes, high blood cholesterol, smoking, and positive family history are the major risk factors for atherosclerosis and coronary artery disease. Medications could stop atherosclerosis development to some degree, but without the lifestyle changes, the patient could not expect significant improvement. We couldn\u2019t have an unhealthy lifestyle and wait for a magical pill to erase and turn over at once, the years of unhealthy living. Therefore, regular exercise, stress relief, smoking cutoff, and a healthy diet are the cornerstone of a patient well being. Diet should be reduced in red and fat meat, processed food, and cholesterol, but reach in sea fish, olive oil, vegetables, and omega-3-acids. Some physicians recommend a glass of red wine a day, but excessive alcohol intake could severely affect your health.[\/vc_column_text][\/vc_column][vc_column width=&#8221;7\/12&#8243;][vc_single_image image=&#8221;394&#8243; img_size=&#8221;full&#8221;][\/vc_column][vc_column][\/vc_column][\/vc_row][vc_row full_width=&#8221;stretch_row&#8221; type=&#8221;vc_default&#8221; css=&#8221;.vc_custom_1589130427361{padding-bottom: 50px !important;}&#8221;][vc_column][vc_raw_html]JTNDc3BhbiUyMGlkJTNEJTIyYm9sZXN0aS16YWxpc3Rha2ElMjIlMjBzdHlsZSUzRCUyMnBvc2l0aW9uJTNBJTIwcmVsYXRpdmUlM0IlMjB0b3AlM0ElMjAtMTAwcHglM0IlMjIlM0UlM0MlMkZzcGFuJTNF[\/vc_raw_html]<div id=\"ultimate-heading-51416a3498156c3c7\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-51416a3498156c3c7 uvc-2145  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-51416a3498156c3c7 h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"font-weight:bold;margin-bottom:20px;\">MITRAL VALVE<\/h2><\/div><\/div>[vc_column_text]The Mitral valve is located between the left atrium and ventricle. Valve has two leaflets that are closed during the heart contraction providing the blood ejection in the aorta. During the heart relaxation, mitral leaflets open and let the blood to fill the left ventricle. That is how the mitral valve regulates the unidirectional blood flow through the left heart chambers. There two primary mitral valve dysfunctions. Leaflets open incompletely in the mitral valve stenosis,\u00a0 while in mitral insufficiency their closure \u00a0is compromised.[\/vc_column_text][\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_column_text css=&#8221;.vc_custom_1595543805311{margin-top: 20px !important;}&#8221;]<strong>Mitral valve stenosis <\/strong>used to be the leading cause of mitral disease in the pre-antibiotic era. Widespread antibiotic use, reduced the incidence of streptococcus bacteria infection and rheumatic fever, therefore. Unfortunately, rheumatic fever remains still a significant cause of mitral disease in undeveloped countries today.<\/p>\n<p><strong>Mitral valve insufficiency or regurgitation <\/strong>is the main form of mitral disease today. Due to degenerative disease, tendinous chordae gets elongated and eventually rupture, resulting in mitral valve prolapse. Prolapsed leaflet makes the valve incompetent, allowing the blood to regurgitate back into the left atrium. In cases of valve infection, or sometimes in acute myocardial infarction, the mitral valve prolapse and insufficiency have a sudden onset. Such a severe regurgitation is generally a medical emergency.<\/p>\n<p>In chronic ischemic mitral valve insufficiency, the valve anatomy itself is preserved, but the coaptation is compromised by severe left ventricle dysfunction due to an old myocardial infarction.[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;598&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column][vc_column][vc_row_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;523&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_column_text css=&#8221;.vc_custom_1595543814943{margin-top: 20px !important;}&#8221;]Grace to the anatomy of the mitral valve, there is generally enough valve tissue to make the valve repair feasible. An experienced surgical team could repair more than 95 % of degenerative mitral valve disease. In ischemic or rheumatic disease, the mitral repair is still possible, but long term results are inferior comparing to degenerative mitral valve repair.<\/p>\n<p>The echocardiography s a main diagnostic tool for the mitral valve disease. It could be done by a transthoracic probe applied on a chest wall or by a transesophageal probe from the esophagus, which provides a better view of mitral valve anatomy. \u00a0The echocardiography grades the severity of the mitral insufficiency. Mitral regurgitation up to 2+ is considered hemodynamically insignificant and needs no further treatment appart of regular follow-up. Mitral insufficiency grade 3+ and 4 + is hemodynamically significant and has to be operated. In the mitral valve stenosis, the mean pressure gradient over 10 mmHg and valve orifice area inferior to 1 cm<sup>2<\/sup> is considered significant and should generally be operated.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column][vc_column_text css=&#8221;.vc_custom_1595543876317{margin-top: 20px !important;}&#8221;]Sometimes it is not possible to repair the mitral valve, and we have to replace it.<\/p>\n<p>The symptoms in chronic mitral insufficiency appear when the heart function starts to deteriorate. Patients could experience effort dyspnea or heart arrhythmias that are worsening according to myocardial dysfunction level. In advanced stages, shortness of bread is present even during daily physical activity or in rest. Mitral valve repair surgery should be therefore performed in early, asymptomatic stages of the disease to preserve heart function. Acute mitral regurgitation is poorly supported and is generally a surgical emergency.[\/vc_column_text][\/vc_column][\/vc_row][vc_row full_width=&#8221;stretch_row&#8221; type=&#8221;vc_default&#8221; css=&#8221;.vc_custom_1588627120952{padding-bottom: 50px !important;}&#8221;][vc_column]<div id=\"ultimate-heading-4466a3498156c49f\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-4466a3498156c49f uvc-1322  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-4466a3498156c49f h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"font-weight:bold;margin-bottom:20px;\">AORTIC VALVE<\/h2><\/div><\/div>[\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_column_text]The aortic valve is located between the left ventricle and the ascending aorta. The aortic valve has three tiny leaflets and opens during the ventricle contraction, allowing blood to ejection into the aorta. During the myocardial relaxation, valve closure prevents blood regurgitation back into the left ventricle. There are two main aortic valve dysfunctions, the aortic valve stenosis and insufficiency.<\/p>\n<p>Aortic stenosis is a mainly degenerative disease that develops during the years in the same patients. Leaflets get rigid and less mobile and calcified eventually along with the aortic valve annulus. The heart compensates for increased pumping demands due to stenosis by myocardial hypertrophy. Patients are generally asymptomatic during this period. Symptoms onset is a sign that myocardium could not compensate the aortic stenosis anymore and are getting to fail.[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;604&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column][vc_column][vc_row_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;512&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_column_text]Systolic heart murmur over the aortic valve, and the following symptoms are clear evidence of existing aortic stenosis:[\/vc_column_text]<div class=\"standard-number-list list-divider bullet-top\"><ol>\n<li>Sinkope &#8211;\u00a0 sudden loss of consciousness<\/li>\n<li>Chest angina \u2013 chest pain like in coronary disease<\/li>\n<li>Heart failure signs &#8211; shortness of breath during exercise or in rest<\/li>\n<\/ol>\n<\/div>[vc_column_text css=&#8221;.vc_custom_1595544236252{margin-top: 20px !important;}&#8221;]The symptom onset announces the terminal disease stage. Life expectancy with the emergence of syncope or chest angina is around 5 years, while those with heart failure signs have a life expectancy of \u00a02 years. Therefore, it is a priority to diagnose and operate aortic stenosis while the heart function is still preserved. Aortic valve replacement is the treatment of choice in aortic valve stenosis.<\/p>\n<p>A small image demonstrates a widely opened aortic valve in systole. Thick and calcified leaflets have restricted motion and do not open completely.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column width=&#8221;2\/3&#8243;][vc_column_text]Leaflet closure is compromised in the aortic valve insufficiency allowing the blood to regurgitate back into the left ventricle. Similar to other valve diseases, such a volume overload dilates the left ventricle that eventually fails. Patients better tolerate chronic aortic valve insufficiency compared to the aortic stenosis. Anyway, valve replacement or repair are treatments of choice.<\/p>\n<p>Acute aortic insufficiency, along with a high temperature, is highly suspicious of bacterial endocarditis. This a severe, most frequently bacterial valve infection that requires immediate hospitalization, antibiotic treatment, and valve replacement surgery. \u00a0\u00a0If a new-onset aortic valve insufficiency is followed by a sharp, excruciating chest pain that spreads from chest to the back or legs, the patient is probably suffering from an acute aortic dissection. That is, of course, a surgical emergency that has to be operated almost immediately to prevent fatal aortic rupture.[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;517&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column][vc_column][vc_row_inner][vc_column_inner width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;468&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;402&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_column_text]Surgical treatment is a gold standard in aortic valve disease. Medication could reduce symptoms but without the surgery heart failure is inevitable. Either mechanical or biological prosthesis could replace the aortic valve. The mechanical prosthesis is durable but requires lifetime anticoagulation therapy. Tissue valves are made either of the bovine pericardium or from porcine valve tissue. They have limited durability, but need no lifetime anticoagulation and are implanted in older patients, generally those above 65 years.[\/vc_column_text][\/vc_column_inner][vc_column_inner][\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column][vc_row_inner][vc_column_inner]<div id=\"ultimate-heading-18056a3498156c69d\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-18056a3498156c69d uvc-9550  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-18056a3498156c69d h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"font-weight:bold;margin-bottom:20px;\">AORTIC VALVE REPAIR<\/h2><\/div><\/div>[\/vc_column_inner][vc_column_inner width=&#8221;2\/3&#8243;][vc_column_text]Aortic valve repair is by war the best solution in aortic valve disease. We are preserving the patient&#8217;s valve and make it fully functional, with almost no foreign material implanted. We repair mostly regurgitant aortic valves since stenosis is almost impossible to reconstruct.[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;403&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column_inner][vc_column_inner]<div id=\"ultimate-heading-73996a3498156c797\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-73996a3498156c797 uvc-8331  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-73996a3498156c797 h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"font-weight:bold;margin-bottom:20px;\">TAVI PROCEDURA<\/h2><\/div><\/div>[\/vc_column_inner][vc_column_inner width=&#8221;2\/3&#8243;][vc_column_text]TAVI. Transcatheter Aortic Valve Implantation is an interventional aortic valve replacement without the surgery. Biological or tissue prosthesis is implanted using a system of catheters placed through the femoral artery. Older and high-risk patients are the best candidates for TAVI.[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;404&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column_inner][\/vc_row_inner][vc_column_text]<\/p>\n<div class=\"hr-thin\"><\/div>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row full_width=&#8221;stretch_row&#8221; type=&#8221;vc_default&#8221; css=&#8221;.vc_custom_1589130539746{padding-bottom: 50px !important;}&#8221;][vc_column][vc_raw_html]JTNDc3BhbiUyMGlkJTNEJTIyYm9sZXN0aS1hb3J0ZSUyMiUyMHN0eWxlJTNEJTIycG9zaXRpb24lM0ElMjByZWxhdGl2ZSUzQiUyMHRvcCUzQSUyMC0xMDBweCUzQiUyMiUzRSUzQyUyRnNwYW4lM0U=[\/vc_raw_html]<div id=\"ultimate-heading-4136a3498156c861\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-4136a3498156c861 uvc-3349  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-4136a3498156c861 h1'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h1 style=\"font-weight:bold;margin-bottom:20px;\">AORTA<\/h1><\/div><\/div>[\/vc_column][vc_column]<div id=\"ultimate-heading-99436a3498156c92d\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-99436a3498156c92d uvc-9938  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-99436a3498156c92d h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"font-weight:bold;margin-bottom:20px;\">ANATOMY<\/h2><\/div><\/div>[\/vc_column][vc_column width=&#8221;7\/12&#8243;][vc_column_text css=&#8221;.vc_custom_1595873276434{margin-top: 20px !important;}&#8221;]Aorta is the major and the biggest artery in the human body. Aorta emerges directly from the left ventricle and the aortic valve, and after that branches to deliver the blood to the brain and other organs. Aorta is exposed to high pressure and volume load during the left ventricle contraction and blood ejection. The thoracic aorta has three segments. The ascending aorta is the aortic portion that emerges directly from a heart. At the level of a collar bone, it continues as an aortic arch, and thereafter downward as descending aorta. Bellow, the diaphragm level aorta continues as an abdominal aorta. Coronary arteries are the first two branches of the ascending aorta, while the brain and arm vessels branch out from the aortic arch. Abdominal aorta branches perfuse abdominal organs and kidneys and terminate by iliac arteries that perfuse the legs.[\/vc_column_text][\/vc_column][vc_column width=&#8221;5\/12&#8243;][vc_single_image image=&#8221;405&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; onclick=&#8221;link_image&#8221;][\/vc_column][vc_column][vc_row_inner][vc_column_inner width=&#8221;1\/2&#8243;][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;]<div id=\"ultimate-heading-72116a3498156c9f8\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-72116a3498156c9f8 uvc-68  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-72116a3498156c9f8 h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"font-weight:bold;margin-bottom:20px;\">AORTIC ANEURISM<\/h2><\/div><\/div>[\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;524&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; css=&#8221;.vc_custom_1597244626726{padding-right: 80px !important;padding-left: 80px !important;}&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243; css=&#8221;.vc_custom_1588703148154{padding-top: 20px !important;}&#8221;][vc_column_text css=&#8221;.vc_custom_1595873325081{margin-top: 20px !important;}&#8221;]Aortic aneurism is a significant aortic dilatation. A healthy thoracic aorta diameter is up to 50 mm, and dilatation over 50 mm is considered an aneurism. Degeneration of the aortic wall tissue is the leading cause of the aneurism. That could be due to aging or to a congenital connective tissue disease, like in Marfan or Ehler-Danlos syndrome, for example. Aneurisms are rarely symptomatic, and therefore frequently discovered accidentally during some other chest diagnostic procedure. Generally, echocardiography and MSCT scans are the main diagnostic tools.<\/p>\n<p>A sudden rise in blood pressure could result in aortic aneurism rupture. According to the Laplace law, the increased diameter increases the pressure on the vessel wall. Therefore, the probability of aneurism rupture rise with its width as well. Surgical treatment is indicated if aneurism diameter is above 55 mm, or even less if another cardiac surgery procedure is performed.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column]<div id=\"ultimate-heading-90786a3498156cad6\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-90786a3498156cad6 uvc-568  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-90786a3498156cad6 h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"font-weight:bold;margin-bottom:20px;\">AORTIC DISSECTION<\/h2><\/div><\/div>[\/vc_column][vc_column width=&#8221;1\/2&#8243;][vc_column_text css=&#8221;.vc_custom_1595873344970{margin-top: 20px !important;}&#8221;]Aortic dissection is a surgical emergency that happens when a sudden rise in blood pressure tears up an aorta from inside. That is an entry point for blood flow to enter and dissect throughout the aortic wall. Dissection most frequently starts at the ascending aorta and spread out after that. Sharp, excruciating chest pain radiates interscapular or down the legs, is the main symptom of aortic dissection. Without the surgery, most patients will die due to aortic rupture.[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;595&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column][vc_column][vc_row_inner][vc_column_inner][vc_raw_html]JTNDc3BhbiUyMGlkJTNEJTIydXJvZGplbmUtbWFuZSUyMiUyMHN0eWxlJTNEJTIycG9zaXRpb24lM0ElMjByZWxhdGl2ZSUzQiUyMHRvcCUzQSUyMC0xMDBweCUzQiUyMiUzRSUzQyUyRnNwYW4lM0U=[\/vc_raw_html]<div id=\"ultimate-heading-69996a3498156cba8\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-69996a3498156cba8 uvc-9524  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-69996a3498156cba8 h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"font-weight:bold;margin-bottom:20px;\">CONGENITAL HEART DISEASE IN ADULTS<\/h2><\/div><\/div>[vc_column_text css=&#8221;.vc_custom_1588704547890{margin-top: 20px !important;}&#8221;]Urodjene sr\u010dane mane kod odraslih osoba su urodjeni defekti sr\u010dane anatomije koji nisu ometali normalan razvoj organizma do odraslog doba, tako da ranije ili nisu bili otkriveni ili jo\u0161 uvek nije bilo potrebe za njihovim le\u010denjam.[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;408&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;]<div class=\"standard-arrow bullet-top\"><p>Following congenital heart diseases, do not affect growth and body development seriously and therefore, could be diagnosed in adults.<\/p>\n<ul>\n<li><strong>Atrial septal defect (ASD) \u2013 The secundum type.<\/strong> That is a congenital defect of the interatrial septum that allows blood flow between the left and right atria. In the majority of adults, ASD is asymptomatic and found accidentally. Depending on the size, defect either affects heart function or allow eventually venous blood clots to pass and embolism the arteries. That is why we have to close them. Percutaneous closure devices are used to close moderate size defects with nice landing rim for the device. Surgical treatment is an option for the defect that is not suitable for percutaneous intervention.<\/li>\n<li><strong>Atrial septal defect (ASD) with mitral leaflet cleft \u2013 the primum type<\/strong>. Interatrial defect in primum type ASD is positioned in lower septum along with anterior mitral cleft. Surgery is the only option for primum type ASD. The defect is closed by a bovine pericardial patch along with the mitral valve repair.<\/li>\n<\/ul>\n<\/div>[\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column]<div class=\"standard-arrow list-divider bullet-top\"><ul>\n<li><strong>Ventricular septal defect &#8211; VSD<\/strong>. Congenital VSD is rare in adults. It is located in the membranous interventricular septum and should be closed surgically or percutaneously.<\/li>\n<li><strong>Persistent ductus arterious (PDA).<\/strong> Ductus arteriosus is a fetal communication between the pulmonary artery and the aorta that closes during childbirth. If still opened in adults, PDA raises the risk of bacterial valve infection, pulmonary hypertension, or heart failure and needs to be closed, therefore. It could be closed by surgery or percutaneously by specially designed coiling devices.<\/li>\n<li><strong>Ebstein anomaly <\/strong>is a congenital malformation of a tricuspid valve in which their leaflets are adherent to the right ventricle or displaced down, reducing the size of the right ventricle and making right atrium very large. Tricuspid valve malfunction, along with altered right heart chamber anatomy, results in right heart failure and has to be operated.<\/li>\n<li><strong>Aortic coarctation <\/strong>is congenital stenosis of a descending aorta. Patients suffer from upper body hypertension, the risk for coronary artery disease, valve infections, aortic aneurysms, and rupture or heart failure. Surgery is indicated when the pressure gradient over the coarctation is greater than 30 mmHg.<\/li>\n<\/ul>\n<p>Ovo su samo naj\u010de\u0161\u0107e mane kod odraslih koje se mogu uspe\u0161no le\u010diti hirur\u0161kim ili interventnim putem. Potrebno je znati da prisustvo ve\u0107ine urodjenih mana kod odraslih zahteva antibiotsku prevenciju bakterijkog endokarditisa (odlazak kod zubara i sl.) Za urodjene mane kod dece treba kontaktirati isklju\u010divo pedijatrijskog kardiologa i kardiohirurga.<\/p>\n<\/div>[\/vc_column][vc_column][vc_raw_html]JTNDc3BhbiUyMGlkJTNEJTIyb3N0YWxvJTIyJTIwc3R5bGUlM0QlMjJwb3NpdGlvbiUzQSUyMHJlbGF0aXZlJTNCJTIwdG9wJTNBJTIwLTEwMHB4JTNCJTIyJTNFJTNDJTJGc3BhbiUzRQ==[\/vc_raw_html]<div id=\"ultimate-heading-69686a3498156ce88\" class=\"uvc-heading ult-adjust-bottom-margin ultimate-heading-69686a3498156ce88 uvc-7354  uvc-heading-default-font-sizes\" data-hspacer=\"no_spacer\"  data-halign=\"left\" style=\"text-align:left\"><div class=\"uvc-heading-spacer no_spacer\" style=\"top\"><\/div><div class=\"uvc-main-heading ult-responsive\"  data-ultimate-target='.uvc-heading.ultimate-heading-69686a3498156ce88 h2'  data-responsive-json-new='{\"font-size\":\"\",\"line-height\":\"\"}' ><h2 style=\"font-weight:bold;margin-bottom:20px;\">HEART TUMORS<\/h2><\/div><\/div>[vc_column_text]Around 75 % of heart tumors are benign, and approximately 50% of them are myxomas. Malignant tumors are rare and mostly secondary due to distant malignancy with heart metastasis.<\/p>\n<div class=\"hr-thin\"><\/div>\n<p>Mixomas are the most common heart tumors. They are benign and could be present as an inherited disease in 5%, or as a sporadic form in 95% of cases. They are generally located and attached to a left atrium by a broad pedicle that allows them to float during the heart contractions. Mixomas are rarely symptomatic and therefore found accidentally during routine echocardiography check-up. Symptoms, if present, are caused by either embolization by tumor particles, or syncope due to valve orifice obstruction. Symptomatic myxomas are surgical emergency, while asymptomatic ones should be operated upon diagnosis to prevent future complications.<\/p>\n<div class=\"hr-thin\"><\/div>\n<p>Fibroelastomas are small, frondlike tumors covered with tiny filaments that could detach and embolize elsewhere. They are generally located on heart valves that could be repared after tumor resection.[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[vc_row type=&#8221;vc_default&#8221; css=&#8221;.vc_custom_1474218751979{padding-bottom: 50px !important;}&#8221;][vc_column][vc_raw_html]JTNDc3BhbiUyMGlkJTNEJTIyYW5hdG9taWphLWZ1bmtjaWphJTIyJTIwc3R5bGUlM0QlMjJwb3NpdGlvbiUzQSUyMHJlbGF0aXZlJTNCJTIwdG9wJTNBJTIwLTEwMHB4JTNCJTIyJTNFJTNDJTJGc3BhbiUzRQ==[\/vc_raw_html][vc_column_text css=&#8221;.vc_custom_1595543659438{padding-bottom: 20px !important;}&#8221;]The heart is located behind the chest bone and slightly displaced to the left side. It is a hollow muscular organ that is pumping the blood throughout our body. The heart consists of two atria and two ventricles. Four heart valves alternatively open and closes during the heart&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-276","page","type-page","status-publish","hentry","description-off"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>On Heart - Kardiohirurgija.rs<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kardiohirurgija.rs\/en\/on-heart\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"On Heart - Kardiohirurgija.rs\" \/>\n<meta property=\"og:description\" content=\"[vc_row type=&#8221;vc_default&#8221; css=&#8221;.vc_custom_1474218751979{padding-bottom: 50px !important;}&#8221;][vc_column][vc_raw_html]JTNDc3BhbiUyMGlkJTNEJTIyYW5hdG9taWphLWZ1bmtjaWphJTIyJTIwc3R5bGUlM0QlMjJwb3NpdGlvbiUzQSUyMHJlbGF0aXZlJTNCJTIwdG9wJTNBJTIwLTEwMHB4JTNCJTIyJTNFJTNDJTJGc3BhbiUzRQ==[\/vc_raw_html][vc_column_text css=&#8221;.vc_custom_1595543659438{padding-bottom: 20px !important;}&#8221;]The heart is located behind the chest bone and slightly displaced to the left side. It is a hollow muscular organ that is pumping the blood throughout our body. The heart consists of two atria and two ventricles. Four heart valves alternatively open and closes during the heart&hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.kardiohirurgija.rs\/en\/on-heart\/\" \/>\n<meta property=\"og:site_name\" content=\"Kardiohirurgija.rs\" \/>\n<meta property=\"article:modified_time\" content=\"2020-08-19T21:58:55+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"20 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.kardiohirurgija.rs\/en\/on-heart\/\",\"url\":\"https:\/\/www.kardiohirurgija.rs\/en\/on-heart\/\",\"name\":\"On Heart - Kardiohirurgija.rs\",\"isPartOf\":{\"@id\":\"https:\/\/www.kardiohirurgija.rs\/en\/#website\"},\"datePublished\":\"2020-07-22T18:12:02+00:00\",\"dateModified\":\"2020-08-19T21:58:55+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.kardiohirurgija.rs\/en\/on-heart\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.kardiohirurgija.rs\/en\/on-heart\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.kardiohirurgija.rs\/en\/on-heart\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u041f\u043e\u0447\u0435\u0442\u043d\u0430\",\"item\":\"https:\/\/www.kardiohirurgija.rs\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"On Heart\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.kardiohirurgija.rs\/en\/#website\",\"url\":\"https:\/\/www.kardiohirurgija.rs\/en\/\",\"name\":\"Kardiohirurgija.rs\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/www.kardiohirurgija.rs\/en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.kardiohirurgija.rs\/en\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.kardiohirurgija.rs\/en\/#organization\",\"name\":\"Kardiohirurgija.rs\",\"url\":\"https:\/\/www.kardiohirurgija.rs\/en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.kardiohirurgija.rs\/en\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.kardiohirurgija.rs\/wp-content\/uploads\/2020\/07\/logo-symbol-H-190px.png\",\"contentUrl\":\"https:\/\/www.kardiohirurgija.rs\/wp-content\/uploads\/2020\/07\/logo-symbol-H-190px.png\",\"width\":842,\"height\":191,\"caption\":\"Kardiohirurgija.rs\"},\"image\":{\"@id\":\"https:\/\/www.kardiohirurgija.rs\/en\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"On Heart - Kardiohirurgija.rs","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.kardiohirurgija.rs\/en\/on-heart\/","og_locale":"en_US","og_type":"article","og_title":"On Heart - Kardiohirurgija.rs","og_description":"[vc_row type=&#8221;vc_default&#8221; css=&#8221;.vc_custom_1474218751979{padding-bottom: 50px !important;}&#8221;][vc_column][vc_raw_html]JTNDc3BhbiUyMGlkJTNEJTIyYW5hdG9taWphLWZ1bmtjaWphJTIyJTIwc3R5bGUlM0QlMjJwb3NpdGlvbiUzQSUyMHJlbGF0aXZlJTNCJTIwdG9wJTNBJTIwLTEwMHB4JTNCJTIyJTNFJTNDJTJGc3BhbiUzRQ==[\/vc_raw_html][vc_column_text css=&#8221;.vc_custom_1595543659438{padding-bottom: 20px !important;}&#8221;]The heart is located behind the chest bone and slightly displaced to the left side. 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